Small business owners even if the business is home-based should consider getting insurance.
For professional services, there’s malpractice insurance.
For people working in your place of business, consider worker’s compensation insurance. [It is a requirement in many states.]
For overall coverage of your workspace and product, then get general liability insurance.
Keep in mind that you should comparison shop for the insurance but do not be misled to think that your home owner’s insurance will protect you. Besides, that is a personal expense and that would be commingling.
For further information, check out the Insurance Information Institute’s guide for small business insurance.